PU.1 is a hematopoietic transcription factor. It specifically regulates transcription of macrophage and B cell genes in stem cells, ultimately leading to cellular differentiation.
You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Name
The name PU.1 comes from the protein's binding interactions with a purine-rich DNA sequence.
Function
Binding Domain
Disease
Relevance
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
