Growth factors

From Proteopedia

spinqualitylabelsall models Platelet-Derived Growth Factor Receptor (brown and turquoise) complex with Platelet-Derived Growth Factor B (grey and green) (PDB code 3mjg) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Activin receptor 3D structure of the kinase domain of Activin receptor1 (Acvr1) complex with inhibitor shows with the protein including a and a [1]. Water molecule is shown as red sphere. Autocrine motility factor Bone morphogenetic protein Colony-stimulating factor Epidermal growth factor and Epidermal Growth Factor Receptor Ephrin and Ephrin receptor Erythropoietin and Erythropoietin receptor Fibroblast growth factor and Fibroblast growth factor receptor Growth differentiation factor Hepatocyte growth factor and Hepatocyte growth factor receptor Insulin and Insulin receptor Insulin-like growth factor and Insulin-like growth factor receptor IGF1 Interleukin Neurotrophin High affinity nerve growth factor receptor TrkB tyrosine kinase receptor Platelet-derived growth factors and receptors Renalase (RNLS) – Anti-apoptotic survival factor Tumor necrosis factor Tumor necrosis factor receptor Tumor necrosis factor ligand superfamily Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor Transforming Growth Factor and its receptor See also: Hormones and their receptors Receptor

References

1. ↑ Mohedas AH, Wang Y, Sanvitale CE, Canning P, Choi S, Xing X, Bullock AN, Cuny GD, Yu PB. Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. J Med Chem. 2014 Oct 9;57(19):7900-15. doi: 10.1021/jm501177w. Epub 2014 Sep 4. PMID:25101911 doi:http://dx.doi.org/10.1021/jm501177w