1f8v
From Proteopedia
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| , resolution 3.00Å | |||||||
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| Ligands: | , , , | ||||||
| Related: | 2bbv, 1nov
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA
Overview
The 3.0 A resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the T = 3 quasi equivalent capsid lies a dodecahedral cage composed of RNA duplex that accounts for approximately 35% of the single-stranded RNA genome. The highly basic N-terminal regions (residues 7-54) of the subunits, forming pentamers (A subunits) are clearly visible in the density map and make numerous interactions with the RNA cage. The C-terminal segments (residues 394-401) of the A subunits lie in channels near the quasi three-fold axes. Electron cryo-microscopy and image reconstruction of PaV particles clearly show the dodecahedral RNA cage.
About this Structure
1F8V is a Protein complex structure of sequences from Pariacato virus. Full crystallographic information is available from OCA.
Reference
The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA., Tang L, Johnson KN, Ball LA, Lin T, Yeager M, Johnson JE, Nat Struct Biol. 2001 Jan;8(1):77-83. PMID:11135676
Page seeded by OCA on Sun Mar 30 20:18:09 2008
