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Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model
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Categories: 11-beta-hydroxysteroid dehydrogenase | Human | Large Structures | Jordan, S R | Li, V | Zhang, J D | Alpha beta | Drug design | Endoplasmic reticulum | Glycoprotein | Inhibitor | Lipid metabolism | Membrane | Nadp | Oxidoreductase | Polymorphism | Rossmann fold | Signal-anchor | Steroid metabolism | Transmembrane

