Structural highlights
1yfg is a 1 chain structure with sequence from Saccharomyces cerevisiae. The March 2001 RCSB PDB Molecule of the Month feature on Transfer RNA by David S. Goodsell is 10.2210/rcsb_pdb/mom_2001_3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| NonStd Res: | , , , , , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Publication Abstract from PubMed
A significantly improved molecular model of yeast initiator tRNA (ytRNA(iMet) has been prepared that gives insight into the structural basis of eukaryotic initiator tRNA's unique function. This study was made possible by X-ray data collected at synchrotron radiation sources with the newly developed technologies of 'imaging plates' and 'storage phosphors'. These data extend beyond the resolution limit of 4.0 A reported previously to a current limit of 3.0 A and are considerably more accurate. Refinement of the model against the new data (R factor = 21.5%) clearly reveals a novel modification and a set of tertiary interactions involving sequence features characteristic of eukaryotic initiator tRNAs. We hypothesize these to be the structural elements responsible for part of the special function of yeast tRNA(iMET).
The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination.,Basavappa R, Sigler PB EMBO J. 1991 Oct;10(10):3105-11. PMID:1915284[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Basavappa R, Sigler PB. The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination. EMBO J. 1991 Oct;10(10):3105-11. PMID:1915284
