Structural highlights
Function
[OSTF1_HUMAN] Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Reddy S, Devlin R, Menaa C, Nishimura R, Choi SJ, Dallas M, Yoneda T, Roodman GD. Isolation and characterization of a cDNA clone encoding a novel peptide (OSF) that enhances osteoclast formation and bone resorption. J Cell Physiol. 1998 Dec;177(4):636-45. PMID:10092216 doi:<636::AID-JCP14>3.0.CO;2-H http://dx.doi.org/10.1002/(SICI)1097-4652(199812)177:4<636::AID-JCP14>3.0.CO;2-H
