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Introduction
VDAC1 is a protein present in the outer mitochondrial membrane(OMM).Mediate exchange of metabolites between mitochondria and cytoplasma. This protein is involved in several cellular processes.
VDAC1 has been shown to be a regulator of OMM permeability to Ca2+
Disease
Relevance
Structural highlights
Human VDAC1 (hVDAC1) adopts a β-barrel architecture composed of 19 with an located horizontally midway within the pore.
neurodegenerative diseases
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