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User:Anna Postnikova/MAT
From Proteopedia
Contents |
Methionine adenosyltransferase
MAT synthesizes S-adenosylmethionine from the substrates ATP and methionine. ATP isn’t used as a source of energy like it is in other reactions but gets a methionine added onto the 5th carbon while the three phosphate groups are broken down and released from the active sit. This enzyme is conserved and found in many organisms, so it is essential for life. Problems with this enzyme have been shown to cause diseases such as various cancers.
SAM Formation Mechanism
Function
Structure
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