Structural highlights
Function
[GFPS_METMA] Involved in biosynthesis of the polyprenyl side-chain of methanophenazine, an electron carrier utilized for methanogenesis. Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylfarnesyl diphosphate (GFPP). It prefers geranylgeranyl diphosphate (GGPP) and farnesyl diphosphate (FPP) as allylic substrate.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Ogawa T, Yoshimura T, Hemmi H. Geranylfarnesyl diphosphate synthase from Methanosarcina mazei: Different role, different evolution. Biochem Biophys Res Commun. 2010 Feb 26;393(1):16-20. doi:, 10.1016/j.bbrc.2010.01.063. Epub 2010 Jan 25. PMID:20097171 doi:http://dx.doi.org/10.1016/j.bbrc.2010.01.063
