Structural highlights
3qvz is a 4 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Related: | 3qvy, 3qw0, 3qw1, 3hni, 3iq6 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Publication Abstract from PubMed
Here, we report that the approach of metal-templated ligand synthesis can be applied to construct a dimeric protein assembly ((BMOE)RIDC1(2)), which is stabilized by noncovalent interactions and flexible covalent cross-linkers around the Zn templates. Despite its flexibility, (BMOE)RIDC1(2) selectively binds Zn(II) over other divalent metals and undergoes dimerization upon metal binding. Such simultaneous fulfillment of plasticity and selectivity is a hallmark of cellular signaling events that involve ligand/metal-induced protein dimerization.
Templated Construction of a Zn-Selective Protein Dimerization Motif.,Salgado EN, Brodin JD, To MM, Tezcan FA Inorg Chem. 2011 Jun 7. PMID:21648390[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Salgado EN, Brodin JD, To MM, Tezcan FA. Templated Construction of a Zn-Selective Protein Dimerization Motif. Inorg Chem. 2011 Jun 7. PMID:21648390 doi:10.1021/ic200746m
