Function
Ribokinase (RK) catalyzes the first step of ribose metabolism by phosphorylating it at the O5' position [1]. ATP serves as the co-substrate of RK.
Disease
Relevance
Structural highlights
Upon forming a ternary complex of RK, ribose and nucleotide the RK dimer changes its open form to a closed one. The ribose substrate interacts with residues Lys43 and Thr30
Ribokinase 3D structures
Ribokinase 3D structures