Function
N-acetylneuraminate lyase or N-acetylneuraminic acid aldolase (NANL) is a class I aldolase which reversibly catalyses the cleavage of N-acetylneuraminic acid (salisilic acid) to N-acetylmannosamine and pyruvate[1].
Disease
Relevance
NANL catalyses the rate-limiting step of two biocatalytic reactions producing salicylic acid in industry[2].
Structural highlights
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3D structures of N-acetylneuraminate lyase
N-acetylneuraminate lyase 3D structures
