Structural highlights
7zjx is a 10 chain structure with sequence from Cricket paralysis virus, Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , , , , , , , , , , , , , , , , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Disease
[SEBP2_HUMAN] Short stature-delayed bone age due to thyroid hormone metabolism deficiency. The disease is caused by variants affecting the gene represented in this entry.
Function
[SEBP2_HUMAN] Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
