4dir

Structural highlights

Function

[S10A5_HUMAN] Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites.^[1]

See Also

• S100 protein

References

1. ↑ Schafer BW, Fritschy JM, Murmann P, Troxler H, Durussel I, Heizmann CW, Cox JA. Brain S100A5 is a novel calcium-, zinc-, and copper ion-binding protein of the EF-hand superfamily. J Biol Chem. 2000 Sep 29;275(39):30623-30. PMID:10882717 doi:http://dx.doi.org/10.1074/jbc.M002260200