1iiu

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spinqualitylabelsall models PDB ID 1iiu Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
, resolution 2.50Å
Ligands:	,
Related:	1AQB, 1HBP, 1HBQ, 1RBP
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Chicken plasma retinol-binding protein (RBP)

Overview

The crystal structure of the specific carrier of retinol (retinol-binding protein, RBP) purified from chicken plasma has been determined (space group P2(1)2(1)2(1), with a=46.06(5) A, b=53.56(6) A, c=73.41(8) A, and one protein molecule in the asymmetric unit). Despite being obtained from a species phylogenetically distant from mammals, chicken holoRBP has an overall structure that closely resembles the previously determined structures of mammalian holoRBPs. The lack in chicken RBP of eight carboxy-terminal amino acid residues characteristic of mammalian RBPs does not significantly affect the protein structure. A distinctive feature of the avian protein is a better definition of the loop 63-67, close to the opening of the beta-barrel cavity accommodating the retinol molecule, which is rather disordered in the structures of mammalian RBPs.

About this Structure

1IIU is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Structure of chicken plasma retinol-binding protein., Zanotti G, Calderone V, Beda M, Malpeli G, Folli C, Berni R, Biochim Biophys Acta. 2001 Nov 26;1550(1):64-9. PMID:11738088

Page seeded by OCA on Sun Mar 30 21:20:28 2008