The androgen receptor (AR) belongs to the steroid hormone group nuclear receptor family with the estrogen, progesterone, glucocorticoid and mineralcorticoid receptor.
AR mediate the actions of testosterone and a more biologically active form, dihydrotestosterone (DHT), which are the male sex hormones required for development of the male reproductive system and secondary sexual characteristics. This receptor is expressed in a diverse range of tissues, because they have significant biological actions in many systems.
Structure
Function
Structural highlights
3D Structures of androgen receptor
drugs
