Introduction

Structure

Antigen Binding Site

The binding of an antigen to the human B Cell receptor is identical to other common soluble antibodies (such as IgG). The antibody portion of the B Cell Receptor consists of two heavy chains and two light chains. The heavy chains interact via the constant fragment (Fc). The two heavy chains branch and individually interact with their respective light chain making two Fab fragments which each contain a variable region (Fv) that binds a specific antigen.

Heavy Chain Intractions (Iga and IgB)

Transmembrane Interactions

Function

Proposed Conformational Changes

Signal Pathway