From Proteopedia
proteopedia link proteopedia link Fragment bound to H.influenza NAD dependent DNA ligase
Structural highlights
4ucs is a 1 chain structure with sequence from "bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896 . Full crystallographic information is available from OCA . For a guided tour on the structure components use FirstGlance . Ligands: , Related: 4uco , 4ucr , 4uct , 4ucu , 4ucv Activity: DNA ligase (NAD(+)) , with EC number 6.5.1.2 Resources: FirstGlance , OCA , PDBe , RCSB , PDBsum , ProSAT
Function
[DNLJ_HAEIN ] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity).
See Also
Categories : Bacterium influenzae lehmann and neumann 1896 Large Structures Boriack-Sjodin, P A Brassington, C Carcanague, D Embrey, K Eyermann, C J Giacobbe, R A Gingipali, L Gowravaram, M Hale, M Harang, J Howard, T Ioannidis, G Jahic, H Kutschke, A Laganas, V A Loch, J Miller, M D Murphy-Benenato, K E Oguto, H Otterbein, L Patel, S J Shapiro, A B Ligase
