Structural highlights
4x57 is a 4 chain structure with sequence from Arath. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | |
| Gene: | UBC8, UBC4A, At5g41700, MBK23.24 (ARATH), MUB3, At4g24990, F13M23.130 (ARATH) |
| Activity: | Ubiquitin--protein ligase, with EC number 6.3.2.19 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[UBC8_ARATH] Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.[1] [MUB3_ARATH] May serve as docking site to facilitate the association of other proteins to the plasma membrane.
See Also
References
- ↑ Kraft E, Stone SL, Ma L, Su N, Gao Y, Lau OS, Deng XW, Callis J. Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Plant Physiol. 2005 Dec;139(4):1597-611. PMID:16339806 doi:http://dx.doi.org/139/4/1597
