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Structural highlights

Function

[NRP1_ARATH] Acts as histone H2A/H2B chaperone in nucleosome assembly, playing a critical role for the correct expression of genes involved in root proliferation and patterning. Required with NRP2 for the maintenance of cell proliferation and differentiation in postembryonic root growth. Involved in both intramolecular and intermolecular somatic homologous recombination.^{[1] [2] [3]}

References

1. ↑ Zhu Y, Dong A, Meyer D, Pichon O, Renou JP, Cao K, Shen WH. Arabidopsis NRP1 and NRP2 encode histone chaperones and are required for maintaining postembryonic root growth. Plant Cell. 2006 Nov;18(11):2879-92. Epub 2006 Nov 22. PMID:17122067 doi:http://dx.doi.org/10.1105/tpc.106.046490
2. ↑ Zhu Y, Dong A, Shen WH. Chromatin remodeling in Arabidopsis root growth. Plant Signal Behav. 2007 May;2(3):160-2. PMID:19704743
3. ↑ Gao J, Zhu Y, Zhou W, Molinier J, Dong A, Shen WH. NAP1 family histone chaperones are required for somatic homologous recombination in Arabidopsis. Plant Cell. 2012 Apr;24(4):1437-47. doi: 10.1105/tpc.112.096792. Epub 2012 Apr, 24. PMID:22534127 doi:http://dx.doi.org/10.1105/tpc.112.096792