Structural highlights
5e68 is a 2 chain structure with sequence from "bacillus_typhi"_schroeter_1886 "bacillus typhi" schroeter 1886. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , |
| NonStd Res: | |
| Related: | 1joe |
| Gene: | luxS, STY2943, t2714 ("Bacillus typhi" Schroeter 1886) |
| Activity: | S-ribosylhomocysteine lyase, with EC number 4.4.1.21 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[LUXS_SALTI] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).[HAMAP-Rule:MF_00091]
