Structural highlights
Function
[HOL1_ARATH] S-adenosyl-L-methionine-dependent methyltransferase. Involved in glucosinolate metabolism and defense against phytopathogens. Highly reactive to thiocyanate (NCS(-)) derived from myrosinase-mediated hydrolysis of glucosinolates upon tissue damage.[REFERENCE:8][1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Nagatoshi Y, Nakamura T. Arabidopsis HARMLESS TO OZONE LAYER protein methylates a glucosinolate breakdown product and functions in resistance to Pseudomonas syringae pv. maculicola. J Biol Chem. 2009 Jul 17;284(29):19301-9. doi: 10.1074/jbc.M109.001032. Epub 2009, May 6. PMID:19419967 doi:10.1074/jbc.M109.001032