Sm-like protein

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spinqualitylabelsall models Sm1 7-member ring dimer complex with RNA, UMP and Ca+2 (green) ions 1m8v Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Sm-like proteins are ring-shaped oligomers of 6-7 members which show nucleic acid-binding activity[1]. In eukaryotes 7 sm-like proteins (LSm2p-LSm8p) are associated with U6 snRNA[2]. For details on Sm1 of Archaeoglobus fulgidus see AF-Sm1. For details on the human protein see Lsm.

3D Structures of Sm-like protein

Updated on 06-April-2022

References

1. ↑ Valentin-Hansen P, Eriksen M, Udesen C. The bacterial Sm-like protein Hfq: a key player in RNA transactions. Mol Microbiol. 2004 Mar;51(6):1525-33. PMID:15009882
2. ↑ Bouveret E, Rigaut G, Shevchenko A, Wilm M, Seraphin B. A Sm-like protein complex that participates in mRNA degradation. EMBO J. 2000 Apr 3;19(7):1661-71. PMID:10747033 doi:10.1093/emboj/19.7.1661