Structural highlights
Function
HBCL1_METS5 Involved in the 3-hydroxypropionate/4-hydroxybutyrate cycle which incorporates carbon dioxide into cellular carbon. Catalyzes the ligation of coenzyme A (CoA) to 4-hydroxybutyrate (4HB). It can also use butyrate, valerate, propionate, acetate and 3-hydroxybutyrate (3HB) as substrates.[1]
References
- ↑ Hawkins AS, Han Y, Bennett RK, Adams MW, Kelly RM. Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea. J Biol Chem. 2013 Feb 8;288(6):4012-22. PMID:23258541 doi:10.1074/jbc.M112.413195
