1oyt
From Proteopedia
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| , resolution 1.67Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , | ||||||
| Gene: | F2 (Homo sapiens) | ||||||
| Activity: | Thrombin, with EC number 3.4.21.5 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED FLUORINATED INHIBITOR
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
1OYT is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions., Olsen JA, Banner DW, Seiler P, Obst Sander U, D'Arcy A, Stihle M, Muller K, Diederich F, Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2507-11. PMID:12800172
Page seeded by OCA on Sun Mar 30 22:52:22 2008
