Structural highlights
Function
C562_ECOLX Electron-transport protein of unknown function.NK2R_HUMAN This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.[1]
References
- ↑ Cyr C, South V, Saltzman A, Felder S, Ricca GA, Jaye M, Huebner K, Kagan J, Croce CM, Schlessinger J, et al.. Cloning, expression of the human substance K receptor, and analysis of its role in mitogenesis. Ann N Y Acad Sci. 1991;632:426-7. PMID:1659297 doi:10.1111/j.1749-6632.1991.tb33144.x