Structural highlights
Publication Abstract from PubMed
A crystalline biohybrid with a 4 : 1 protein : cucurbituril mass ratio is presented. This result was achieved by engineering additional cucurbit[7]uril (Q7) binding sites into a beta-propeller protein. In contrast to the parent protein, Q7-controlled assembly of the engineered variant occurred in solution, as evidenced by NMR and SAXS measurements.
Engineered assembly of a protein-cucurbituril biohybrid.,Guagnini F, Engilberge S, Ramberg KO, Perez J, Crowley PB Chem Commun (Camb). 2020 Jan 2;56(3):360-363. doi: 10.1039/c9cc07198a. PMID:31825399[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Guagnini F, Engilberge S, Ramberg KO, Perez J, Crowley PB. Engineered assembly of a protein-cucurbituril biohybrid. Chem Commun (Camb). 2020 Jan 2;56(3):360-363. doi: 10.1039/c9cc07198a. PMID:31825399 doi:http://dx.doi.org/10.1039/c9cc07198a
