Structural highlights
Disease
[GDAP1_HUMAN] Charcot-Marie-Tooth disease type 2H;Autosomal recessive intermediate Charcot-Marie-Tooth disease type A;Autosomal dominant Charcot-Marie-Tooth disease type 2K;Autosomal recessive Charcot-Marie-Tooth disease with hoarseness;Charcot-Marie-Tooth disease type 4A. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
Function
[GDAP1_HUMAN] Regulates the mitochondrial network by promoting mitochondrial fission.[1]
References
- ↑ Niemann A, Ruegg M, La Padula V, Schenone A, Suter U. Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J Cell Biol. 2005 Sep 26;170(7):1067-78. doi: 10.1083/jcb.200507087. Epub 2005, Sep 19. PMID:16172208 doi:http://dx.doi.org/10.1083/jcb.200507087
