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Publication Abstract from PubMed

The plague-causing bacterium Yersinia pestis utilizes a contact-dependent (type III) secretion system (T3SS) to transport virulence factors from the bacterial cytosol directly into the interior of mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. The type III secretion apparatus is composed of 20-25 different Yersinia secretion (Ysc) proteins. We report here the structure of YscE, the smallest Ysc protein, which is a dimer in solution. The probable mode of oligomerization is discussed.

Crystal structure of the Yersinia type III secretion protein YscE.,Phan J, Austin BP, Waugh DS Protein Sci. 2005 Oct;14(10):2759-63. PMID:16195558^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.