Structural highlights
Publication Abstract from PubMed
The crystal structure of d(CACACG).d(CGTGTG) was solved to a resolution of 2.05 A in space group P2(1). The duplex assumes the left-handed Z-DNA structure. The presence of two A.T base pairs in the hexamer does not greatly affect the conformation. The most significant changes compared with the regular structure of Z-DNA are in the values of twist in the central portion of the helix. This variation, as well as others in the values of roll, inclination etc., follow the pattern observed previously in the structure of d(CGCACG).d(CGTGCG).
The structure of d(CACACG).d(CGTGTG).,Venkadesh S, Mandal PK, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jan 1;65(Pt, 1):8-13. Epub 2008 Dec 25. PMID:19153446[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Venkadesh S, Mandal PK, Gautham N. The structure of d(CACACG).d(CGTGTG). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jan 1;65(Pt, 1):8-13. Epub 2008 Dec 25. PMID:19153446 doi:10.1107/S1744309108037706
