Structural highlights
Publication Abstract from PubMed
The title oligonucleotide and many related dodecamers have been extensively studied alone and as DNA-drug complexes. In practically all cases they were found to crystallize in the same space group, stabilized by interactions among the terminal guanine bases. Here we report new packing interactions (R3) in the presence of Ca2+. The oligonucleotides interact by placing their terminal guanines in the narrow groove of a neighbor molecule, an interaction which had never been found in dodecamers.
The structure of the most studied DNA fragment changes under the influence of ions: a new packing of d(CGCGAATTCGCG).,Liu J, Malinina L, Huynh-Dinh T, Subirana JA FEBS Lett. 1998 Nov 6;438(3):211-4. PMID:9827547[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Liu J, Malinina L, Huynh-Dinh T, Subirana JA. The structure of the most studied DNA fragment changes under the influence of ions: a new packing of d(CGCGAATTCGCG). FEBS Lett. 1998 Nov 6;438(3):211-4. PMID:9827547
