Structural highlights
Publication Abstract from PubMed
Crystal structures of the hexanucleotide d(CACGCG).d(CGCGTG) were determined in two crystal lattices when different concentrations of the counterion Mn(2+) were used in crystallization. The availability of Mn(2+) during the crystallization process appears to play an important role in inducing different crystal packings that lead to crystals belonging to the two space groups P2(1) and P6(5). Analysis of the molecular interactions of Mn(2+) with the Z-form duplexes shows direct coordination to the purine residues G and A.
Interactions of Mn(2+) with a non-self-complementary Z-type DNA duplex.,Mandal PK, Venkadesh S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1420-6., doi: 10.1107/S1744309112041759. Epub 2012 Nov 14. PMID:23192018[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Mandal PK, Venkadesh S, Gautham N. Interactions of Mn(2+) with a non-self-complementary Z-type DNA duplex. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1420-6., doi: 10.1107/S1744309112041759. Epub 2012 Nov 14. PMID:23192018 doi:http://dx.doi.org/10.1107/S1744309112041759
