2l6r

Structural highlights

Function

HCP_LAMBD Plays a role in morphogenesis of the virion head after genome packaging. Presumably interacts with the portal vertex to stabilize the packaged DNA within the head after packaging. Probably binds to the head-tail connector protein FII.^{[1] [2] [3]}

References

1. ↑ Murialdo H, Xing X, Tzamtzis D, Haddad A, Gold M. The product of the bacteriophage lambda W gene: purification and properties. Biochem Cell Biol. 2003 Aug;81(4):307-15. doi: 10.1139/o03-059. PMID:14569303 doi:http://dx.doi.org/10.1139/o03-059
2. ↑ Cardarelli L, Pell LG, Neudecker P, Pirani N, Liu A, Baker LA, Rubinstein JL, Maxwell KL, Davidson AR. Phages have adapted the same protein fold to fulfill multiple functions in virion assembly. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14384-9. Epub 2010 Jul 26. PMID:20660769
3. ↑ Casjens S, Horn T, Kaiser AD. Head assembly steps controlled by genes F and W in bacteriophage lambda. J Mol Biol. 1972 Mar 14;64(3):551-63. PMID:5022189