1sfo
From Proteopedia
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| , resolution 3.61Å | |||||||
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| Ligands: | , , , , , , , , , | ||||||
| Activity: | DNA-directed RNA polymerase, with EC number 2.7.7.6 | ||||||
| Related: | 1R9S, 1R9T
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX
Overview
The structure of an RNA polymerase II-transcribing complex has been determined in the posttranslocation state, with a vacancy at the growing end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand/loop network. Formation of the network must occur in the transition from abortive initiation to promoter escape.
About this Structure
1SFO is a Protein complex structure of sequences from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entry 1R9R. Full crystallographic information is available from OCA.
Reference
Structural basis of transcription: separation of RNA from DNA by RNA polymerase II., Westover KD, Bushnell DA, Kornberg RD, Science. 2004 Feb 13;303(5660):1014-6. PMID:14963331
Page seeded by OCA on Sun Mar 30 23:41:25 2008
