Structural highlights
Function
BEND6_HUMAN Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis (PubMed:23571214).[1]
References
- ↑ Dai Q, Andreu-Agullo C, Insolera R, Wong LC, Shi SH, Lai EC. BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells. Development. 2013 May;140(9):1892-902. PMID:23571214 doi:10.1242/dev.087502