7r2m

Structural highlights

Function

A0A4W2GEM6_BOBOX Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.[ARBA:ARBA00003833]SYJ2B_HUMAN