4q1q

Structural highlights

Function

TIBA_ECOH1 Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation.^{[1] [2]}

References

1. ↑ Lindenthal C, Elsinghorst EA. Enterotoxigenic Escherichia coli TibA glycoprotein adheres to human intestine epithelial cells. Infect Immun. 2001 Jan;69(1):52-7. PMID:11119488 doi:http://dx.doi.org/10.1128/IAI.69.1.52-57.2001
2. ↑ Elsinghorst EA, Weitz JA. Epithelial cell invasion and adherence directed by the enterotoxigenic Escherichia coli tib locus is associated with a 104-kilodalton outer membrane protein. Infect Immun. 1994 Aug;62(8):3463-71. PMID:8039917