From Proteopedia

SARS-CoV-2 De Novo Designed Minibinders

spinqualitylabelsall models SARS-CoV-2 Spike Protein Bound to Minibinders (PDB 7jzl) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image This is test text to fill space. Contents 1 Introduction 2 Function 3 Stability 4 Binding Site Introduction COVID-19 Function The minibinder associates with the SARS-CoV-2 spike protein binding domain for ACE-2 before it reaches a host cell. Stability Placeholder Image to be Replaced Structure sourced from original source paper Longxing et al.[1] Binding Site

References

1. ↑ Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls AC, Park YJ, Strauch EM, Stewart L, Diamond MS, Veesler D, Baker D. De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science. 2020 Oct 23;370(6515):426-431. PMID:32907861 doi:10.1126/science.abd9909

Student Contributors

Matt Pereira, Giavanna Yowel, and Shae Bailey