4gr1

From Proteopedia

Revision as of 02:38, 31 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:4gr1.gif


PDB ID 4gr1

Drag the structure with the mouse to rotate
, resolution 2.4Å
Ligands: , ,
Activity: Glutathione-disulfide reductase, with EC number 1.8.1.7
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



THE BINDING OF THE RETRO-ANALOGUE OF GLUTATHIONE DISULFIDE TO GLUTATHIONE REDUCTASE


Overview

The retro-analogue of glutathione disulfide was bound to the GSSG binding site of crystalline glutathione reductase. The binding mode revealed why the analogue is a very poor substrate in enzyme catalysis. The observed binding mode difference between natural substrate and retro-analogue is explained.

About this Structure

4GR1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The binding of the retro-analogue of glutathione disulfide to glutathione reductase., Janes W, Schulz GE, J Biol Chem. 1990 Jun 25;265(18):10443-5. PMID:2355009

Page seeded by OCA on Mon Mar 31 05:38:54 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4gr1"
Personal tools