1cof

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Image:1cof.jpg

Template:STRUCTURE 1cof

YEAST COFILIN, ORTHORHOMBIC CRYSTAL FORM


Overview

Cofilin, a ubiquitous 15,000 M(r) protein, plays a central role in regulating cytoskeletal dynamics. Cofilin binds to actin monomers and filaments, and has a pH-dependent actin severing activity. The structure will allow for a detailed analysis of cofilin function.

About this Structure

1COF is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Structure determination of yeast cofilin., Fedorov AA, Lappalainen P, Fedorov EV, Drubin DG, Almo SC, Nat Struct Biol. 1997 May;4(5):366-9. PMID:9145106 Page seeded by OCA on Fri May 2 12:56:51 2008

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