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1lxd

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Template:STRUCTURE 1lxd

CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN


Overview

The Ras-interacting domains of the the protein-kinase Raf and the Ral guanine nucleotide dissociation stimulator, RalGDS, lack extensive sequence similarity, but their overall three-dimensional structures are very similar to each other. Mutational analysis indicated that three residues in the RalGDS domain are critical for its interaction with Ras.

About this Structure

1LXD is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of the Ras-interacting domain of RalGDS., Huang L, Weng X, Hofer F, Martin GS, Kim SH, Nat Struct Biol. 1997 Aug;4(8):609-15. PMID:9253406 Page seeded by OCA on Sat May 3 00:23:32 2008

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