1rbp

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Image:1rbp.gif

Template:STRUCTURE 1rbp

CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION


Overview

Human serum retinol binding protein (RBP) in complex with retinol has been crystallographically refined to an R-factor of 18.1% with 2A resolution data. The protein topology results in an anti-parallel beta-barrel that encapsulates the retinol ligand. A detailed description of the protein and the binding site is provided. Our structural work has helped to define a family of proteins, many of which are carrier proteins for smaller ligand molecules. We describe the structural basis for the conservation of sequence within the family.

About this Structure

1RBP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystallographic refinement of human serum retinol binding protein at 2A resolution., Cowan SW, Newcomer ME, Jones TA, Proteins. 1990;8(1):44-61. PMID:2217163 Page seeded by OCA on Sat May 3 07:18:37 2008

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