2flb

From Proteopedia

Revision as of 01:01, 4 May 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2flb.gif

Template:STRUCTURE 2flb

Discovery of a Novel Hydroxy Pyrazole Based Factor IXa Inhibitor


Contents

Overview

Synthesis and biological data of a novel selective and efficacious factor IXa inhibitor are described along with its crystal structure in factor VIIa.

Disease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]

About this Structure

2FLB is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery of novel hydroxy pyrazole based factor IXa inhibitor., Vijaykumar D, Sprengeler PA, Shaghafi M, Spencer JR, Katz BA, Yu C, Rai R, Young WB, Schultz B, Janc J, Bioorg Med Chem Lett. 2006 May 15;16(10):2796-9. Epub 2006 Feb 17. PMID:16487703 Page seeded by OCA on Sun May 4 04:01:39 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2flb"
Personal tools