3bqp
From Proteopedia
Crystal Structure of Human Saposin D (orthorhombic)
Overview
Saposin D is a sphingolipid activator protein required for the lysosomal breakdown of ceramide to a fatty acid and sphingosine by acid ceramidase. The crystal structure of saposin D has been determined in two different crystal forms, resulting in a total of six crystallographically independent views of this small 80-amino-acid protein. All of the structures are highly similar and reveal the monomeric form of the saposin fold previously seen in the crystal structures of saposins A and C. Saposin D is slightly more compact than the related saposins A and C owing to a slight repositioning of the ;stem' and ;hairpin' regions of the protein.
About this Structure
3BQP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structures of the human ceramide activator protein saposin D., Popovic K, Prive GG, Acta Crystallogr D Biol Crystallogr. 2008 May;64(Pt 5):589-94. Epub 2008, Apr 19. PMID:18453694 Page seeded by OCA on Thu May 22 22:35:30 2008
