1xxq

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Template:STRUCTURE 1xxq

Structure of a mannose-specific jacalin-related lectin from Morus nigra


Overview

The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins.

About this Structure

1XXQ is a Single protein structure of sequence from Morus nigra. Full crystallographic information is available from OCA.

Reference

Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose., Rabijns A, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Rouge P, FEBS J. 2005 Jul;272(14):3725-32. PMID:16008570 Page seeded by OCA on Sat May 3 15:38:27 2008

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