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3cam

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Template:STRUCTURE 3cam

Crystal structure of the cold shock domain protein from Neisseria meningitidis


Overview

The structure of the cold-shock domain protein from Neisseria meningitidis has been solved to 2.6 A resolution and shown to comprise a dimer formed by the exchange of two beta-strands between protein monomers. The overall fold of the monomer closely resembles those of other bacterial cold-shock proteins. The neisserial protein behaved as a monomer in solution and was shown to bind to a hexathymidine oligonucleotide with a stoichiometry of 1:1 and a K(d) of 1.25 microM.

About this Structure

3CAM is a Single protein structure of sequence from Neisseria meningitidis mc58. Full crystallographic information is available from OCA.

Reference

Structure of the cold-shock domain protein from Neisseria meningitidis reveals a strand-exchanged dimer., Ren J, Nettleship JE, Sainsbury S, Saunders NJ, Owens RJ, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Apr 1;64(Pt, 4):247-51. Epub 2008 Mar 21. PMID:18391418 Page seeded by OCA on Wed May 7 09:00:01 2008

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