2dsy

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Template:STRUCTURE 2dsy

Crystal structure of TTHA0281 from thermus thermophilus HB8


Overview

TTHA0281 is a hypothetical protein from Thermus thermophilus HB8 that belongs to an uncharacterized protein family, UPF0150, in the Pfam database and to COG1598 in the National Center for Biotechnology Information Database of Clusters of Orthologous Groups. The X-ray crystal structure of the protein was determined by a multiple-wavelength anomalous dispersion technique and was refined at 1.9 A resolution to a final R factor of 18.5%. The TTHA0281 monomer adopts an alpha-beta-beta-beta-alpha fold and forms a homotetramer. Based on the properties and functions of structural homologues of the TTHA0281 monomer, the TTHA0281 protein is speculated to be involved in RNA metabolism, including RNA binding and cleavage.

About this Structure

2DSY is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structure of a UPF0150-family protein from Thermus thermophilus HB8., Okazaki N, Kumei M, Manzoku M, Kuramitsu S, Shirouzu M, Shinkai A, Yokoyama S, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt, 3):173-7. Epub 2007 Feb 23. PMID:17329807 Page seeded by OCA on Sun May 4 01:13:50 2008

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