2ibf

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Template:STRUCTURE 2ibf

Contents

Human vinculin's head domain (Vh1, residues 1-258) in complex with two vinculin binding sites of Shigella flexneri's IpaA (residues 565-587)

Template:ABSTRACT PUBMED 17932491

Disease

Known disease associated with this structure: Cardiomyopathy, dilated, 1W OMIM:[193065]

About this Structure

2IBF is a 3 chains structure of sequences from Homo sapiens and Shigella flexneri. Full crystallographic information is available from OCA.

Reference

Vinculin binding in its closed conformation by a helix addition mechanism., Nhieu GT, Izard T, EMBO J. 2007 Oct 31;26(21):4588-96. Epub 2007 Oct 11. PMID:17932491

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