2p8k

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Template:STRUCTURE 2p8k

Selective screening and design to identify inhibitors of Leishmania major pteridine reductase 1.

Template:ABSTRACT PUBMED 18245389

About this Structure

2P8K is a Single protein structure of sequence from Leishmania major. Full crystallographic information is available from OCA.

Reference

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development., Cavazzuti A, Paglietti G, Hunter WN, Gamarro F, Piras S, Loriga M, Allecca S, Corona P, McLuskey K, Tulloch L, Gibellini F, Ferrari S, Costi MP, Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1448-53. Epub 2008 Feb 1. PMID:18245389

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