This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3e8r
From Proteopedia
Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
Template:ABSTRACT PUBMED 18835710
About this Structure
3E8R is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: Optimization of the S3' pocket., Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X, Bioorg Med Chem Lett. 2008 Sep 13. PMID:18835710
Page seeded by OCA on Wed Oct 22 10:51:38 2008
Categories: ADAM 17 endopeptidase | Homo sapiens | Single protein | Orth, P. | Alternative splicing | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Protease | Sh3-binding | Tace adam17 zn-endopeptidase | Transmembrane | Zinc | Zymogen
